The main access roads are:
The Regional Route n.6 "della Murgia Centrale" connects the A14 highway exit of Canosa di Puglia with the SP 138 "Cavoni".
The SP. 234 (formerly SS 170 "Strada del Castel del Monte") departs from the SP 231 (formerly SS 98) at Ruvo di Puglia and after about 40 kilometers, in the town of Minervino Murge it flows into the SP 230 (formerly SS 97).
The SP. 230 (formerly SS 97 "delle Murge") connects Minervino with Canosa and Andria, going into the SP 231 (formerly SS 98), while from the South side with Spinazzola and then Gravina in Puglia.
The SP. 64 "Minervino Lavello" connects Minervino with the nearby Basilicata region.
The SP. 155 "Minervino Montegrosso" connects Minervino with the inhabited center of Montegrosso (fraction of Andria).
Minervino Murge is linked by the Ferrovie dello Stato (Trenitalia) to the Spinazzola - Barletta section.
The railway station is far about 500 m from Casa Pistacchio.
The closest airport is Bari Palese, about 70 kilometers from Casa Pistacchio.